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The Center for Fertility and Gynecology

Intralipid Therapy Offers New Hope for Patients with Infertility

For patients who have struggled with infertility, intralipid therapy may offer a new opportunity for a successful pregnancy. Intralipids are a fatty acid derived from soy which can combat overactive white blood cell activity and prevent rejection of a potential embryo. At the Center for Fertility & Gynecology in Los Angeles, CA, we are proud to offer this new treatment option for patients who have had difficulties achieving successful pregnancy. Dr. Michael Vermesh has used this therapy with over 150 women, allowing the majority of them to become pregnant and successfully deliver a child. 

"Intralipids is the way to go... for recurring pregnancy loss and for IVF failure..."

Dr. Vermesh discuss how intralipid therapy works and the benefits of this unique new treatment.

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How It Can Help

During a normal pregnancy, the body minimizes its normal response to a foreign body so that it does not attack the half of the embryo which does not belong to the woman. More specifically, natural killer (NK) cell activity is reduced in early pregnancy to allow the embryo to implant and grow. 

However, for some women, this reduction in NK cell activity does not occur. Instead, these cells become over-activated and cause failed implantation or miscarriage. This autoimmune system response can result in a long, difficult, and emotionally painful road to fertility. 

Research suggests that intralipids reduce the NK cell activity, combating the effects of the overactive autoimmune response. Basically, intralipids can increase your chance of successful embryo implantation and reduce the risk of miscarriage. Dr. Vermesh is proud to offer intralipid therapy as a method for helping women who have not found success with other treatments. 

IV bag of intralipids
Before starting fertility treatment, women will undergo intralipid therapy to prepare their bodies for a possible embryo. 

The Benefits of Intralipids

In the past, intravenous immunoglobulin (IVIG) was often used for women dealing with recurrent miscarriage or other difficulties with in-vitro fertilization (IVF). IVIG uses a mixture of antibodies to address the autoimmune conditions behind infertility. However, IVIG is expensive and can cause an allergic reaction in certain patients.

In contrast, intralipids are:

  • Organic: There are no chemicals used in intralipid therapy. The compound is made from the fatty acids in soy. 
  • Safe: Unlike IVIG, none of our patients have reported side effects or allergic reactions to intralipid therapy.
  • Affordable: Intralipids fulfill the same purpose as IVIG at a fraction of the cost.

Is Intralipid Therapy Right for Me?

The best way to find out if this therapeutic technique is right for you is to schedule an appointment at the Center for Fertility and Gynecology. Generally, we recommend intralipid therapy for patients who:

  • Have had repeated miscarriages
  • Have been unsuccessful with other fertility treatments
  • Are dealing with immunological infertility

During your consultation, Dr. Vermesh and Dr. Toloubeydokhti will perform a full fertility evaluation to identify the cause of your infertility issues. For some women, issues with implantation and miscarriage can be due to structural issues with their uterus, such as a uterine septum, or concerns with the embryos themselves. If this is the case, intralipid therapy is unlikely to help. We can perform all of your testing in our laboratory and help you decide what option is best for you. 

Opening New Routes to Parenthood

At the Center for Fertility and Gynecology, we understand how stressful and overwhelming dealing with infertility can be. If you have tried unsuccessfully to build your family, we may be able to find a solution for you. Learn more about intralipid therapy by contacting our practice online or calling one of our multiple locations today. 

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